The two-year-old who ‘looks pregnant’ due to a rare cancer

The two-year-old who ‘looks pregnant’: Toddler suffers from a rare cancer that has caused her abdomen to swell up and left her with just a 25% chance of surviving

  • Cleo Keenan developed an abnormal swelling in her midriff earlier this year
  • Has adrenal carcinoma, which affects the outer layer of the adrenal glands 
  • Endured chemo to shrink the tumour for surgery, but may be unsuccessful 

A toddler is battling a rare and aggressive cancer that has left her ‘looking pregnant’.

Cleo Keenan, of Blackpool, suddenly developed an abnormal swelling in her midriff earlier this year, which doctors put down to a hormone imbalance she has suffered from before.

It was not until she endured severe abdominal pain that a CT scan revealed the two-year-old is suffering from stage three adrenal carcinoma, which affects the outer layer of the adrenal glands – found just above the kidneys. 

Following her diagnosis, Cleo started chemotherapy and blood transfusions. She now requires more treatment to shrink the tumour before undergoing surgery to remove it. 

However, her parents Shannon Latham, 23, and Ryan Keenan, 26, have been told their ‘little warrior’ has just a 25-to-35 per cent chance of surviving, with the tumour returning in 80 per cent of cases.  

Cleo Keenan (left) is battling a rare and aggressive cancer that has left her ‘looking pregnant’. Since being diagnosed on April 1, the toddler (pictured right in hospital) has endured chemotherapy and blood transfusions, and requires more treatment before surgery

The youngster’s mother Shannon Latham calls Cleo her ‘little fighter’, adding she is ‘so strong’. Ms Latham is pictured with her daughters Emelia, five, Cleo and Ellie-Mae, four (left-to-right)

Speaking of her daughter’s symptoms, Ms Latham said: ‘She looked like she was pregnant. I was getting more and more concerned.’

Cleo was taken to a medical centre in February, where doctors initially dismissed her symptoms as being nothing new. 

‘Because of her hormone changes, they thought she had a hormone imbalance,’ Ms Latham said.

Cleo was then rushed to Blackpool Victoria Hospital’s A&E department last month with a severe stomach ache.

The youngster was given a CT scan, which revealed the huge tumour inside her abdomen.

She was taken to Manchester Children’s Hospital the next day for further tests. Two weeks later, at the start of April, she received the devastating diagnosis.

‘It was such a shock when we found out,’ Ms Latham said. ‘It’s just begun to sink in because she’s so young and she’s such a bright child.

‘She had always been absolutely healthy. She was like any other two-year-old.’

Doctors initially thought Cleo’s swollen abdomen (left and right) was due to a hormonal balance she has suffered from before. A scan revealed the cancer after she endured pain

Cleo required urgent treatment, which began the day after she was diagnosed.

Ms Latham, who is also mother to Emelia, five, and Ellie-Mae, four, said: ‘On April 2 she started chemotherapy and she was on that for four days. It was draining. 

‘The chemo started making her ill, and she’s had to have a blood transfusion and injections of so many different medications.’ 

‘She’s gone from being a normal happy child to a really poorly little thing and it’s really difficult to see.

‘I’m sat there every day with her just watching her go down and down.

‘I wish there was a way I could take it away from her and fight it. That’s what’s hard. I can’t take it away from her.’

Despite everything she has endured, the youngster (left) is managing to stay positive. Her mother claims the tumour is ‘grapefruit sized’ and pressing on her internal organs

Cleo is due to undergo further chemotherapy before an operation to remove the tumour and her affected adrenal gland later this year.

However, her mother claims there is an 80 per cent chance the tumour will return even after surgery.  


Adrenal carcinoma is a ‘very rare’ cancer that starts in the outer layer of the adrenal glands.

The adrenal glands produce hormones and are located above the kidneys.

Adrenal carcinoma can cause too many of these hormones to be made, leading to symptoms. 

For example, too much cortisol can affect the body’s blood sugar balance.

And excessive amounts of aldosterone can upset water and salt levels, as well as blood pressure.  

Adrenal carcinoma’s cause is often unclear. Some people are born with a genetic mutation that puts them at risk. 

Symptoms can include:

  • Raised blood pressure
  • Thirst
  • Passing urine more frequently
  • Muscle cramps
  • Weight gain, particularly in the abdomen
  • Muscle wasting of the limbs
  • Fat accumulation at the base of the neck
  • Swelling of the face
  • Mild diabetes
  • Abnormal hair growth on the face, arms and upper back 

Treatment depends on the size of the tumour and whether it has spread.

Adrenal carcinoma is often fast growing and only diagnosed at a late stage, which makes treatment tricky.

It can include, however, surgery to remove the affected gland, as well as radiotherapy and chemo.

Source: Cancer Research UK 

‘All we can do is remain positive and happy,’ Ms Latham said. ‘It keeps a smile on Cleo’s face. That’s what we want for the whole time she’s being treated; for her to keep smiling.

‘We just say to ourselves this is just another chapter of her life.

‘We are shrinking the tumour with chemotherapy at the moment and once it’s small enough they’re going to remove it.

‘There’s an 80 per cent chance of it recurring, but that means there’s a 20 per cent chance it won’t.’

Writing on her fundraising page, Ms Latham claims her daughter’s tumour is ‘the size of a grapefruit’ and is ‘causing her intestines to be squashed to the left side’.

She claims Cleo’s heart rate has gone up as a result of the growth, which also leaves her feeling ‘full all the time’ and ‘peeing constantly’ because it presses on her bladder.

But despite everything she has endured, the youngster manages to stay positive.  

‘Cleo is still smiling through every single day,’ Ms Latham said. ‘She still laughs and jokes, and the hospital has been amazing – she’s been having fun in their playroom. She’s a little warrior. 

‘When I see her smiling when I’m with her it makes everything much easier.

‘Cleo is bubbly and independent. She’s really advanced for her age. She’s not like other two-year-olds. Her speech is amazing. She speaks like a four or five-year-old. 

‘She’s a great child and a great little fighter. She’s been so strong in hospital.’ 

Ms Latham credits her partner for helping her get through this difficult time. 

‘Ryan rings me every day and when he asked me about Cleo he also makes sure I’m eating and everything,’ she said. ‘He’s my rock at the minute.’

The family has set up a Facebook page – Cleo’s Chapter – to document the toddler’s cancer fight.

They have also launched an online fundraiser to help pay for their regular journeys between Blackpool and Manchester Children’s Hospital, where Cleo is being treated. 

Donate here. 

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